The LAMA3/Laminin 5 alpha 3 Antibody, Biotin Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to LAMA3. This antibody recognizes Human antigen. The LAMA3/Laminin 5 alpha 3 Antibody, Biotin Conjugated has been validated for the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes